Perhaps you are already aware of just how things work here. On the forum, bad news travels faster than good news or a good experience. Do not lose sleep over problems you have yet to experience. But there is certainly nothing wrong with being well informed, assembling a statistic of likely issues and perhaps learning to recognize them before they become critical. I believe your original post to represent this perspective.
Over the past nearly 40 years of driving these cars, I have treated most critical issues as they arise. The exception is the routine maintenance items that I can do myself or have attended to by the local garage when appropriate. For instance, I have had 3 wagons. Each required one of the front drive-shafts to be replaced. I do not know why, but that is hardly mentioned in this forum as a common problem of the wagon. I have had one fuel pump go bad (ML430), but no other fuel related issues in the 6 used E-class cars this family has gone through (W210, W211, valid for this discussion).
On the other hand, I have had idler pulleys, belt-tensioners and water pumps die. Crank position sensors and alternator regulators too. These are now all replaced around the 10 year / 100+K mile point. None of this should be an excuse to ditch the car, as none of them account for serious money in repairs, but they all will happen to you if you take it to 200K miles.
Having owned a couple with the 'air-ride' system, I find its difference from the conventional suspension noteworthy and pleasurable, but I'm old and perhaps less arrogantly critical than others. To call it 'overrated' is a personal opinion, perhaps held by one who does not own a car so equipped. Yes, there are alternatives to it, but you must first be able to account for the quality of workmanship of the installer who is willing to modify the car in a critical area. Yes, this system will eventually give you trouble, and first signs will likely show up (or down) in the winter if you live where it gets cold. Personally, I have chosen to have them repaired when they gave me issues, and the Arnott product has proven to be a viable OEM replacement. However, consider that I have been accused of throwing my money away on occasion, but mostly by people who do not drive a Mercedes, never mind these particular models.
Do replace the transmission fluid and filter soon. You do not know how the prior driver treated the car.
I hope you find this helpful.