It could be lots of things.
The misfires are in all probability happening all the time. That's why the cel is on.
When they are bad enough the ecu shuts down the cylinders to protect cats, etc. That resets when you restart the car.
My first guess, if you want one, is that your maf is failing. That often will throw myriad and random misfires.
But it could be many other things. If you have been deferring maintenance, you might need plugs and O2 sensors, for example. Or since they are all on the same bank, perhaps a vacuum leak, perhaps a clogged cat.
Some live data would be useful, but that is more diagnostics. That said, I'd probably start by checking for vacuum leaks and be sure I had a good air filter in place, plus taking care of any deferred maintenance.
Thanks Check Codes
>OK makes sense that the cylinder is being shut down, then clears.
>Reading elsewhere I now understand your point about CEL. I thought it came on automatically with codes, but others have lots of codes and no CEL.
>However, if I check for codes, I don't find any, until the CEL comes on and I am down a cylinder
>CEL flashed for the first time last time out, so I guess that is something extra bad
>So, I think I am getting some event the both triggers the P0302 (or more) and shuts down cylinder(s)
-Bad wire short on #2?
-I'm 120k and don't know the plugs were changed.
I overpaid on the car from a widow based on all the care they supposedly took. Body and interior nice, but the breathers and front were covered with oil. Bad sign when superb care doesn't include the oil blank off.