Well, that depends on a few things, mainly what all you've done to it and whether or not you're at any hardware peaks or if the bottleneck is the ECU itself. Is your MAP/MAF signal maxed out? Are your injectors at max duty cycle? Currently running rich or lean? Detonation?
If you are not at max duty cycle and you are not pegging out your MAP/MAF, then the simple route to tuning would be a piggy-back "liar" system like the Apexi or MAF Translator. If you are short fuel or need to upgrade your MAP/MAF, then something like that would work with some adjustment, but the route I went was with a MegaSquirt ECU with integrated MAP sensor, and works with any injectors (high impedance, low impedance) but only supports one-cylinder or a distributor type setup. To get around this I'm using an external distributorless ignition system with a trigger wheel and VR sensor. They have their own EDIS system in development at the moment to integrate into the megasquirt, but won't be ready until early next year and I'm impatient (although may adopt later).

You can read some of my previous posts in this thread for more details on my plans for integrating with the factory ECU.
Currently I have the unit built and connected to the stim tester board, and I'm doing preliminary setup and fuel configurations before installing in the car. I haven't posted many pics in the past few days, but this post just reminded me that I should, so I'll get right on that.

I need to post pics of my trigger wheel and wheel bracket and the ECU among other things. I'm stuck at the office at the moment... perhaps tomorrow.