We've been through this before . . . the other bolded statement does not give free reign to do anything the fed wants. There are other governments within our boundaries.
And, ultimately, the fed promotes art and science through copyrights and patents according to the COTUS. But, I guess all those agencies cited are "good" unconstitutional programs and there's no other way to get them done. Maybe we should send more money to DC for the lobbyists, er, government to control.
Or we could realize that as a Democratic Republic [not a Constitutional Democracy] we have grown up since 1776 and matured as a Nation. And as a Democratic Republic we, the people have given our government representatives the right to make laws on our behalf [I think that is the reason we have that Congress thing]. And those Congressmen and Senators have, for some 230 years been doing just that. Some very good, some very bad, some braindead, some brilliant. But ALL have been scrutinized by the Executive Branch and subject to the Judiciary for review.
As I have said before, the Constitution is a great starting point for a Nation, is serves us well in that role. It is not, however a point by point roadmap, some of the points did not exist in 1776. It is simply an outline. The rest of the tools provided by that same group of guys are responsible for the stack of laws we have now - both good and bad.
Do I like them all, not even remotely. Many are wasteful. But in this time of the US losing patent wars with other countries and the US dropping in academic testing worldwide and the US losing in trade wars and the US falling behind in so many categories, the last thing we need to do is shortchange things like advanced sciences. Corporations are stripping R&D budgets to the bone or offshoring them. We need to push this
country to be great again and we will do so with technological advances. MOST not mentioned in the Constitution.