Surely A Large Human
Date registered: Jun 2006
Vehicle: '08 C219
Location: Between Earth and Mars
Mentioned: 2 Post(s)
Quoted: 482 Post(s)
File format compatibility has nothing to do with hardware. Microsoft has shipped Office versions for quite some time (just released Office 2008). The rest depends on the application in question. It's definitely easier for people to develop for Mac now that it's Intel based, and software support has poured in ever since.
Also, while a bit pokey, Mac's can in fact write to NTFS volumes from external drives. I'm not even sure you need to do anything special - if I did, it was very quick and easy.