Interesting Mr Diesel Benz. I just put tires on the front 2 days ago and have not had the problem since. I just can't fathom that the rotational mass being that significant. I have factory wheels and orig equip size tires. I have owned many other makes and models of cars even with aftermarket wheels and never seen this issue. Thank you for bringing it to my attention.
Mass has nothing to do with it, overall diameter is the problem. Too much deviation front to rear (as in too staggered) and the ESP will activate around corners. I can imagine the ESP control module seeing a slight difference and disabling cruise control.