Date registered: Mar 2006
Vehicle: 2005 CL65 AMG, 2007 Ferrari F430
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What radio do you have now? You can go to my site and see pictures. Just select your car and scroll down. There are three possible (Audio 10/20, Audio 50, COMAND) - If you have anything but the base Audio 10/20, it is not a simple matter of replacing the radio as in the old days. Your car is fiber optic based, and the whole thing would need to be re-wired.
IF you have just the base radio without Bose or Harmon Kardon amplifier, then it is not too difficult.