Date registered: Nov 2006
Vehicle: Oo == oO 98 E320
Location: Nashville, TN
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My guess: Assuming maintenance per the owner's manual you should get 250-300k miles on a gas engine. Some will get a bit less, many will get more. A diesel Mercedes should get you at least 400k, again a few less, some many more miles.
Mercedes generally stay on the road a long time because the body itself is unusually well made and durable. Just remember though, the engine, albeit the biggest/ most expensive component other than the body, is just a fraction of the whole vehicle. Which leads you to everything else! From transmission to climate control, steering to brakes, there are a lot of other things to go just plain wear out. Many cars are abandoned because of these items wearing out & not being replaced than the engine itself. With proper maintenance you could enjoy many miles out of any Mercedes; the preference is indeed for the diesels.
'87 300E: sold after 11years @ 230k & still on the road somewhere in rural Tennessee.
'94 C220 with 93k totalled 10/06 by hit & run broadsiding monster truck: not a scratch or bruise for me